Nexpovio (Selinexor) Medical Equipment & Supplies

1 equipment items found

Nexpovio (Selinexor) - Oral Exportin 1 (XPO1) Inhibitor

Manufactured by:The Menarini Group based inFlorence, ITALY

NEXPOVIO is a first-in-class, oral exportin 1 (XPO1) inhibitor. XPO1 is a nuclear exporter protein that transport from the nucleus to the cytoplasm several proteins, including tumor suppressors, oncogenes, and proteins involved in governing cell growth; it is often overexpressed, and its function mis-regulated in several types of cancers. By inhibiting the XPO1 protein, tumor suppressors proteins ...

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